Downregulation of HLA Class I molecules in the tumour is associated with a poor prognosis in patients with oesophageal squamous cell carcinoma

As antigenic peptides in the context of human leukocyte antigen (HLA) class I molecules are recognised by cytotoxic T lymphocytes (CTL), the downregulation of HLA class I molecules is one of the reasons why tumour cells can evade CTL-mediated anti-tumour immunity. In this study, we investigated HLA...

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Bibliografske podrobnosti
Main Authors: Mizukami, Y, Kono, K, Maruyama, T, Watanabe, M, Kawaguchi, Y, Kamimura, K, Fujii, H
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2008
Teme:
Molecular Diagnostics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579690/
https://ncbi.nlm.nih.gov/pubmed/18841157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604715
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