Oleanolic acid induces relaxation and calcium-independent release of endothelium-derived nitric oxide

BACKGROUND AND PURPOSE: The present study investigated the mechanisms by which oleanolic acid, a component of olive oil, increases release of nitric oxide (NO). EXPERIMENTAL APPROACH: Measurements of isometric tension, NO concentration, or endothelial cell calcium were made in rat isolated mesenteri...

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Detalhes bibliográficos
Main Authors: Rodriguez-Rodriguez, R, Stankevicius, E, Herrera, M D, Østergaard, L, Andersen, M R, Ruiz-Gutierrez, V, Simonsen, U
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579672/
https://ncbi.nlm.nih.gov/pubmed/18622409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.289
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