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Pulmonary hypertension: therapeutic targets within the serotonin system

Pulmonary arterial hypertension (PAH) is characterized by a sustained and progressive elevation in pulmonary arterial pressure and pulmonary vascular remodelling leading to right heart failure and death. Prognosis is poor and novel therapeutic approaches are needed. The serotonin hypothesis of PAH o...

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Autori principali: Dempsie, Y, MacLean, M R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579665/
https://ncbi.nlm.nih.gov/pubmed/18536742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.241
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