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Identification of hot-spot residues in protein-protein interactions by computational docking

BACKGROUND: The study of protein-protein interactions is becoming increasingly important for biotechnological and therapeutic reasons. We can define two major areas therein: the structural prediction of protein-protein binding mode, and the identification of the relevant residues for the interaction...

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Detalhes bibliográficos
Main Authors: Grosdidier, Solène, Fernández-Recio, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579439/
https://ncbi.nlm.nih.gov/pubmed/18939967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-447
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