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Iron-dependent regulation of diphtheria toxin and siderophore expression by the cloned Corynebacterium diphtheriae repressor gene dtxR in C. diphtheriae C7 strains.

A regulatory gene (dtxR) responsible for iron-dependent repression of the toxin (tox) and siderophore genes in Corynebacterium diphtheriae was cloned and characterized. A DNA fragment carrying dtxR repressed expression of a tox-lacZ gene fusion in Escherichia coli DH5 alpha in a high-iron environmen...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Schmitt, M P, Holmes, R K
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257940/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1828057/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.6.1899-1904.1991
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