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Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair

The error-free repair of double-stranded DNA breaks by homologous recombination requires processing of broken ends. These processed ends are substrates for assembly of DNA strand exchange proteins that mediate DNA strand invasion. Here, we establish that human BLM helicase, a member of the RecQ fami...

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Detalhes bibliográficos
Main Authors: Nimonkar, Amitabh V., Özsoy, A. Zeynep, Genschel, Jochen, Modrich, Paul, Kowalczykowski, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579351/
https://ncbi.nlm.nih.gov/pubmed/18971343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809380105
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