Hemolytic and sphingomyelinase activities of Clostridium perfringens alpha-toxin are dependent on a domain homologous to that of an enzyme from the human arachidonic acid pathway.

The N-terminal domain of Clostridium perfringens alpha-toxin, homologous with the nontoxic phospholipase C of Bacillus cereus, was expressed in Escherichia coli and shown to retain all of the phosphatidylcholine hydrolyzing activity of the alpha-toxin, but not the sphingomyelinase, hemolytic, or let...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Infect Immun
Egile Nagusiak: Titball, R W, Leslie, D L, Harvey, S, Kelly, D
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 1991
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257931/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1902199/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.5.1872-1874.1991
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