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Solution structure of the integral human membrane protein VDAC-1 in detergent micelles

The voltage-dependent anion channel (VDAC) mediates trafficking of small molecules and ions across the eukaryotic outer mitochondrial membrane. VDAC also interacts with anti-apoptotic proteins from the Bcl-2 family and this interaction inhibits release of apoptogenic proteins from the mitochondrion....

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Autores principales: Hiller, Sebastian, Garces, Robert G., Malia, Thomas J., Orekhov, Vladislav Y., Colombini, Marco, Wagner, Gerhard
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579273/
https://ncbi.nlm.nih.gov/pubmed/18755977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1161302
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