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Importance of a N-terminal aspartate in the internalization of the neuropeptide Y Y(2) receptor
With human neuropeptide Y Y(2) receptor expressed in the Chinese hamster ovary (CHO) cells, the Asp(35)Ala mutation, and especially the change of Pro(34)Asp(35) to Ala(34)Ala(35), decrease the compartmentalization and strongly accelerate internalization of the receptor. These changes are not associa...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2579264/ https://ncbi.nlm.nih.gov/pubmed/18700141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2008.07.038 |
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