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Synthetic peptide substrates for the immunoglobulin A1 protease from Neisseria gonorrhoeae (type 2).

Neisseria gonorrhoeae secretes protease which inactive human immunoglobulin A1 (IgA1) by cleavage of specific peptide bonds in the hinge region. The type 2 IgA1 protease (EC 3.4.24.13) is secreted as a 169-kDa precursor which undergoes autoproteolysis at three sites (A, B, and C) to release the 106-...

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Bibliographic Details
Main Authors: Wood, S G, Burton, J
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC257921/
https://ncbi.nlm.nih.gov/pubmed/1902197
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