Synthetic low-toxicity muramyl dipeptide and monophosphoryl lipid A replace Freund complete adjuvant in inducing growth-inhibitory antibodies to the Plasmodium falciparum major merozoite surface protein, gp195.

The Plasmodium falciparum major merozoite surface protein (gp195) is a protective antigen against lethal malaria. However, increasing evidence indicates that the efficacy of a malaria vaccine will require a strong adjuvant that is safe for human use. We compared the efficacies of two low-toxicity sy...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Hui, G S, Tam, L Q, Chang, S P, Case, S E, Hashiro, C, Siddiqui, W A, Shiba, T, Kusumoto, S, Kotani, S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257888/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2019429/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.5.1585-1591.1991
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