Leptin therapy for partial lipodystrophy linked to a PPAR-γ mutation

AIMS/HYPOTHESIS: Partial lipodystrophy (PL) is most commonly characterized by loss of subcutaneous fat in the extremities with preservation of truncal fat and is associated with insulin resistance, diabetes and hyperlipidaemia. Recombinant human leptin (rmetHuLeptin) therapy has been shown to be eff...

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Main Authors: Guettier, Jean-Marc, Park, Jean Y., Cochran, Elaine K., Poitou, Christine, Basdevant, Arnaud, Meier, Muriel, Clément, Karine, Magré, Jocelyne, Gorden, Phillip
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2578870/
https://ncbi.nlm.nih.gov/pubmed/18076675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2265.2007.03095.x
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