Genome-wide profiling of PPARγ:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis

The nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) is a key regulator of adipocyte differentiation in vivo and ex vivo and has been shown to control the expression of several adipocyte-specific genes. In this study, we used chromatin immunoprecipitation combined with deep sequ...

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Autors principals: Nielsen, Ronni, Pedersen, Thomas Åskov, Hagenbeek, Dik, Moulos, Panagiotis, Siersbæk, Rasmus, Megens, Eva, Denissov, Sergei, Børgesen, Michael, Francoijs, Kees-Jan, Mandrup, Susanne, Stunnenberg, Hendrik G.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2008
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577787/
https://ncbi.nlm.nih.gov/pubmed/18981474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.501108
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