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Rapid induction of pluripotency genes after exposure of human somatic cells to mouse ES cell extracts

The expression of 4 pluripotency genes (Oct4, Sox2, c-Myc and Klf4) in mouse embryonic fibroblasts can reprogramme them to a pluripotent state. We have investigated the expression of these pluripotency genes when human somatic 293T cells are permeabilised and incubated in extracts of mouse embryonic...

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Detalhes bibliográficos
Main Authors: Bru, Thierry, Clarke, Catriona, McGrew, Michael J., Sang, Helen M., Wilmut, Ian, Blow, J. Julian
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577761/
https://ncbi.nlm.nih.gov/pubmed/18571647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2008.05.009
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