Intracellular and extracellular enzymatic deacylation of bacterial endotoxin during localized inflammation induced by Escherichia coli.

Acyloxyacyl hydrolase (AOAH), an enzyme that removes the secondary acyl chains of gram-negative bacterial lipid A (endotoxin), has been identified previously in human neutrophils and mouse macrophages. We report here that bovine leukocytes also contain AOAH activity. Although bovine AOAH deacylates...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	McDermott, C M, Cullor, J S, Fenwick, B W
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257775/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1987068/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.2.478-485.1991
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