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Plant flavonoid apigenin inactivates Akt to trigger apoptosis in human prostate cancer: an in vitro and in vivo study

Inappropriate activation of phosphatidylinositol 3-kinase–Akt signaling contributes to the development of several human malignancies. Modulation of Akt activity is a strategy that may be valuable in chemopreventive and chemotherapeutic regimens. We have previously demonstrated that apigenin, a plant...

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Hlavní autoři: Kaur, Parminder, Shukla, Sanjeev, Gupta, Sanjay
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577719/
https://ncbi.nlm.nih.gov/pubmed/18725386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn201
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