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Evolution Acts on Enhancer Organization to Fine-Tune Gradient Threshold Readouts

The elucidation of principles governing evolution of gene regulatory sequence is critical to the study of metazoan diversification. We are therefore exploring the structure and organizational constraints of regulatory sequences by studying functionally equivalent cis-regulatory modules (CRMs) that h...

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Detalhes bibliográficos
Main Authors: Crocker, Justin, Tamori, Yoichiro, Erives, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577699/
https://ncbi.nlm.nih.gov/pubmed/18986212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0060263
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