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Vascular Inflammation, Insulin Resistance and Reduced Nitric Oxide Production Precede the Onset of Peripheral Insulin Resistance

OBJECTIVES: Obesity causes inflammation and insulin resistance in the vasculature as well as in tissues involved in glucose metabolism such as liver, muscle, and adipose tissue. To investigate the relative susceptibility of vascular tissue to these effects, we determined the time course over which i...

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Detalhes bibliográficos
Main Authors: Kim, Francis, Pham, Matilda, Maloney, Ezekiel, Rizzo, Norma O., Morton, Gregory J., Wisse, Brent E., Kirk, Elizabeth A., Chait, Alan, Schwartz, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577575/
https://ncbi.nlm.nih.gov/pubmed/18772497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.169722
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