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Striatal and ventral pallidum dynorphin concentrations are markedly increased in human chronic cocaine users

Interest in development of therapeutics targeting brain neuropeptide systems for treatment of cocaine addiction (e.g., κ opioid agonists) is based on animal data showing interactions between the neuropeptides, brain dopamine, and cocaine. In this autopsied brain study, our major objective was to est...

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Detalhes bibliográficos
Main Authors: Frankel, Paul S., Alburges, Mario E., Bush, Lloyd, Hanson, Glen R., Kish, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577569/
https://ncbi.nlm.nih.gov/pubmed/18538358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2008.04.019
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