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Candida albicans UPC2 is transcriptionally induced in response to antifungal drugs and anaerobicity through Upc2p dependent and independent mechanisms.

Many genes in the Candida albicans ergosterol biosynthetic pathway are controlled by the transcriptional activator Upc2p, which is upregulated in the presence of azole drugs and has been suggested to regulate its own transcription by an autoregulatory mechanism. The UPC2 promoter was cloned upstream...

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Bibliografske podrobnosti
Main Authors: Hoot, Samantha J., Oliver, Brian G, White, Theodore C.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577385/
https://ncbi.nlm.nih.gov/pubmed/18757808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.2008/017475-0
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