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Injury and Nucleotides Induce Phosphorylation of Epidermal Growth Factor Receptor: MMP and HB-EGF Dependent Pathway

The early events that occur rapidly after injury trigger signal cascades that are essential for proper wound closure of corneal epithelial cells. We hypothesize that injury releases ATP, which stimulates purinergic receptors and elicits the phosphorylation of epidermal growth factor receptor (EGFR)...

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Detalhes bibliográficos
Main Authors: Boucher, Ilene, Yang, LingLing, Mayo, Courtney, Klepeis, Veronica, Trinkaus-Randall, Vickery
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577227/
https://ncbi.nlm.nih.gov/pubmed/17490650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2007.03.009
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