Genetic immunization with Hantavirus vaccine combining expression of G2 glycoprotein and fused interleukin-2

In this research, we developed a novel chimeric HTNV-IL-2-G2 DNA vaccine plasmid by genetically linking IL-2 gene to the G2 segment DNA and tested whether it could be a candidate vaccine. Chimeric gene was first expressed in eukaryotic expression system pcDNA3.1 (+). The HTNV-IL-2-G2 expressed a 72...

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Detalhes bibliográficos
Main Authors: Hao, Huang, Xiu, Li, Zehua, Zhang, Min, Jia, Hongbo, Hu, Zhihong, Wu, Zhenhua, Zhu, Xiaohong, Wan, Hanju, Huang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577087/
https://ncbi.nlm.nih.gov/pubmed/18940009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-6-15
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