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Evolutionary Patterning: A Novel Approach to the Identification of Potential Drug Target Sites in Plasmodium falciparum

Malaria continues to be the most lethal protozoan disease of humans. Drug development programs exhibit a high attrition rate and parasite resistance to chemotherapeutic drugs exacerbates the problem. Strategies that limit the development of resistance and minimize host side-effects are therefore of...

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Detalhes bibliográficos
Main Authors: Durand, Pierre M., Naidoo, Kubendran, Coetzer, Theresa L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577034/
https://ncbi.nlm.nih.gov/pubmed/18997863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003685
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