Synthesis and characterization of a Pseudomonas aeruginosa alginate-toxin A conjugate vaccine.
Alginate from Pseudomonas aeruginosa 3064 was depolymerized by controlled heating in dilute acid. The resulting depolymerized alginate (Mr less than 60,000) was covalently coupled to toxin A with adipic acid dihydrazide as a spacer molecule and carbodiimide as a linker. The resulting conjugate was c...
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| Published in: | Infect Immun |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
1991
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257703/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1898901/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.1.45-50.1991 |
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