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Mechanistic Dissection of the Enzyme Complexes Involved in Biosynthesis of Lacticin 3147 and Nisin

The thioether rings in the lantibiotics lacticin 3147 and nisin are posttranslationally introduced by dehydration of serines and threonines, followed by coupling of these dehydrated residues to cysteines. The prepeptides of the two-component lantibiotic lacticin 3147, LtnA1 and LtnA2, are dehydrated...

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Main Authors: Kuipers, Anneke, Meijer-Wierenga, Jenny, Rink, Rick, Kluskens, Leon D., Moll, Gert N.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576704/
https://ncbi.nlm.nih.gov/pubmed/18791001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01334-08
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