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Comparative immunogenicity of conjugates composed of the Staphylococcus aureus type 8 capsular polysaccharide bound to carrier proteins by adipic acid dihydrazide or N-succinimidyl-3-(2-pyridyldithio)propionate.

Staphylococcus aureus type 8 capsular polysaccharide (CP) was conjugated either to diphtheria toxoid or to Pseudomonas aeruginosa recombinant exoprotein A by using adipic acid dihydrazide (ADH) or N-succinimidyl-3-(2-pyridyldithio)propionate (SPDP) as the joining reagent. The polysaccharide/protein...

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Fattom, A, Shiloach, J, Bryla, D, Fitzgerald, D, Pastan, I, Karakawa, W W, Robbins, J B, Schneerson, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1992
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257668/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1730492/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.2.584-589.1992
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