A Novel Small Molecule Regulator of Guanine Nucleotide Exchange Activity of the ADP-ribosylation Factor and Golgi Membrane Trafficking

An image-based phenotypic screen was developed to identify small molecule regulators of intracellular traffic. Using this screen we found that AG1478, a previously known inhibitor of epidermal growth factor receptor, had epidermal growth factor receptor-independent activity in inducing the disassemb...

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Hlavní autoři: Pan, Heling, Yu, Jia, Zhang, Lihong, Carpenter, Anne, Zhu, Hong, Li, Li, Ma, Dawei, Yuan, Junying
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
Membrane Transport, Structure, Function, and Biogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576541/
https://ncbi.nlm.nih.gov/pubmed/18799457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806592200
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