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An enzymatic mutant of Shiga-like toxin II variant is a vaccine candidate for edema disease of swine.

Edema disease (ED) of weanling pigs is caused by an infection with Escherichia coli that produces Shiga-like toxin II variant (SLT-IIv). Pathology identical to that caused by ED can be duplicated in pigs that are injected with less than 10 ng of purified SLT-IIv per kg of body weight. Therefore, SLT...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Gordon, V M, Whipp, S C, Moon, H W, O'Brien, A D, Samuel, J E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257653/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1730480/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.2.485-490.1992
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