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Warts is required for PI3K-regulated growth arrest, autophagy and autophagic cell death in Drosophila

BACKGROUND: Cell growth arrest and autophagy are required for autophagic cell death in Drosophila. Maintenance of growth by expression of either activated Ras, Dp110, or Akt is sufficient to inhibit autophagy and cell death in fly salivary glands, but the mechanism that controls growth arrest is unk...

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Autors principals: Dutta, Sudeshna, Baehrecke, Eric H.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576500/
https://ncbi.nlm.nih.gov/pubmed/18818081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.08.052
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