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Pilus Operon Evolution in Streptococcus pneumoniae Is Driven by Positive Selection and Recombination

BACKGROUND: The evolution of bacterial organelles involved in host-pathogen interactions is subject to intense and competing selective pressures due to the need to maintain function while escaping the host immune response. To characterize the interplay of these forces in an important pathogen, we se...

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Autors principals: Muzzi, Alessandro, Moschioni, Monica, Covacci, Antonello, Rappuoli, Rino, Donati, Claudio
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576445/
https://ncbi.nlm.nih.gov/pubmed/18987753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003660
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