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Tethering Forces of Secretory Granules Measured with Optical Tweezers

Fusion of a vesicle with its target membrane is preceded by tethering or docking. However, the physical mechanism of vesicle-tethering is unknown. To study this mechanism, we used eosinophil secretory granules, which undergo stimulated homotypic fusion events inside the cell during degranulation. Us...

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Detalhes bibliográficos
Main Authors: Valero, Vicente, Nevian, Thomas, Ho, Dominik, Lindau, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576405/
https://ncbi.nlm.nih.gov/pubmed/18689450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.132670
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