Response of Pseudomonas aeruginosa to pyocyanin: mechanisms of resistance, antioxidant defenses, and demonstration of a manganese-cofactored superoxide dismutase.

Pseudomonas aeruginosa produces a blue pigment, pyocyanin. Pyocyanin is a redox-active phenazine compound that kills mammalian and bacterial cells through the generation of reactive oxygen intermediates. We examined the mechanisms by which P. aeruginosa resists pyocyanin. [14C]pyocyanin was taken up...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Hassett, D J, Charniga, L, Bean, K, Ohman, D E, Cohen, M S
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1992
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257632/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1730464/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.2.328-336.1992
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