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Generation of human monoclonal antibodies that confer protection against pertussis toxin.

A panel of human monoclonal antibodies reactive with pertussis toxin has been generated by means of Epstein-Barr virus infection. One of these, the 3F11 monoclonal antibody, showed the ability to neutralize in vitro and in vivo the toxic effects of the toxin. Western blot (immunoblot) analysis locat...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Zaccolo, M, Roggero, S, Armellini, D, Pegoraro, L, Rappuoli, R, Malavasi, F
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1992
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257625/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1541543/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.3.1258-1260.1992
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