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High-affinity binding of Clostridium perfringens epsilon-toxin to rat brain.

125I-epsilon-toxin showed high affinity to rat brain homogenates and synaptosomal membrane fractions, having single binding phases with dissociation constants (Kds) of 2.5 and 3.3 nM, respectively. Treatment of synaptosomal membrane fractions with pronase and neuraminidase lowered the binding of the...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Nagahama, M, Sakurai, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1992
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257620/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1541539/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.3.1237-1240.1992
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