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Complex genetic regulation of bone mineral density and insulin-like growth factor-I in C57BL/6J-Chr #(A/J)/NaJ chromosome substitution strains
Low bone mineral density (BMD) is a phenotype associated with osteoporosis and increased risk of fracture. Since 60–80% of variation in BMD is associated with genetic factors, we used the novel approach of chromosome substitution strains (CSS) to identify chromosomes that harbor genes that regulate...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Physiological Society
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575955/ https://ncbi.nlm.nih.gov/pubmed/18682576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.90203.2008 |
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