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Flagellin-stimulated Cl(−) secretion and innate immune responses in airway epithelia: role for p38

Activation of an innate immune response in airway epithelia by the human pathogen Pseudomonas aeruginosa requires bacterial expression of flagellin. Addition of flagellin (10(−7) M) to airway epithelial cell monolayers (Calu-3, airway serous cell-like) increased Cl(−) secretion (I(Cl)) beginning aft...

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Main Authors: Illek, Beate, Fu, Zhu, Schwarzer, Christian, Banzon, Tina, Jalickee, Stephen, Miller, Sheldon S., Machen, Terry E.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575945/
https://ncbi.nlm.nih.gov/pubmed/18658272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90292.2008
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