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Gastrin increases mcl-1 expression in type I gastric carcinoid tumors and a gastric epithelial cell line that expresses the CCK-2 receptor

Elevated serum concentrations of the hormone gastrin are associated with the development of gastric carcinoid tumors, but the mechanisms of tumor development are not fully understood. We hypothesized that the antiapoptotic effects of gastrin may be implicated and have therefore investigated the role...

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Hlavní autoři: Pritchard, D. M., Berry, D., Przemeck, S. M. C., Campbell, F., Edwards, S. W., Varro, A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575912/
https://ncbi.nlm.nih.gov/pubmed/18719002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00015.2008
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