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Ribozyme Catalysis Revisited: Is Water Involved?

Enzymatic catalysis by RNA was discovered 25 years ago, yet mechanistic insights are emerging only slowly. Thought to be metalloenzymes at first, some ribozymes proved more versatile than anticipated when shown to utilize their own functional groups for catalysis. Recent evidence suggests that some...

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Détails bibliographiques
Auteur principal: Walter, Nils G.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575846/
https://ncbi.nlm.nih.gov/pubmed/18158891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.12.001
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