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IFN-γ Regulation of Vacuolar pH, Cathepsin D Processing and Autophagy in Mammary Epithelial Cells

In this study we examined the ability of interferon-γ (IFN-γ) to regulate mammary epithelial cell growth and gene expression, with particular emphasis on two genes: Maspin (a member of serine protease inhibitor superfamily), and the lysosomal aspartyl endopeptidase cathepsin D (CatD). The protein pr...

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Detalhes bibliográficos
Main Authors: Khalkhali-Ellis, Zhila, Abbott, Daniel E., Bailey, Caleb M., Goossens, William, Margaryan, Naira V., Gluck, Stephen L., Reuveni, Moshe, Hendrix, Mary J.C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575810/
https://ncbi.nlm.nih.gov/pubmed/18494001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21814
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