Serotonin(1B) heteroreceptor activation induces an antidepressant-like effect in mice with an alteration of the serotonergic system

OBJECTIVE: We sought to demonstrate whether the specific activation of serotonin(1B) (5-HT(1B)) heteroreceptors by systemic or local administration of the selective 5-HT(1B) receptor agonist anpirtoline could mediate antidepressant-like effects in mice. METHODS: We confirmed the selectivity of actio...

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Main Authors: Chenu, Franck, David, Denis J.P., Leroux-Nicollet, Isabelle, Maître, Erwan Le, Gardier, Alain M., Bourin, Michel
Format: Artigo
Sprog:Inglês
Udgivet: Canadian Medical Association 2008
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575758/
https://ncbi.nlm.nih.gov/pubmed/18982177
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