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The actin cross-linking protein AFAP120 regulates axon elongation in a tyrosine phosphorylation-dependent manner

Growth cone guidance and axon elongation require the dynamic coordinated regulation of the actin cytoskeleton. As the growth cone moves, actin-dependent forces generate tension that enables protrusive activity in the periphery and drives growth cone translocation. This dynamic remodeling of the acti...

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Autores principales: Harder, Jennifer, Xu, Xiaohua, Letourneau, Paul, Lanier, Lorene M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575687/
https://ncbi.nlm.nih.gov/pubmed/18723076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2008.08.036
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