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Suppression of bone morphogenetic protein inhibitors promotes osteogenic differentiation: therapeutic implications

Bone morphogenetic proteins (BMPs) are expressed during osteogenesis and their action is regulated by corresponding BMP inhibitors. Chordin (a well recognized BMP inhibitor) and BMP-2 are expressed during osteogenic differentiation of human mesenchymal stem cells. Chordin inhibition induces human me...

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Bibliografiske detaljer
Main Authors: Heliotis, Manolis, Tsiridis, Eleftherios
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575635/
https://ncbi.nlm.nih.gov/pubmed/18710600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2467
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