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Adjuvants targeting innate and adaptive immunity synergize to enhance tumor immunotherapy
Because of mechanisms of self-tolerance, many tumor-specific CD8 T cells exhibit low avidity for tumor antigens and would benefit from strategies that enhance their numbers and effector function. Here we demonstrate that the combined use of two different types of immune adjuvants, one that directly...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575480/ https://ncbi.nlm.nih.gov/pubmed/18936481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805054105 |
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