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Small-scale copy number variation and large-scale changes in gene expression

The expression dynamics of interacting genes depends, in part, on the structure of regulatory networks. Genetic regulatory networks include an overrepresentation of subgraphs commonly known as network motifs. In this article, we demonstrate that gene copy number is an omnipresent parameter that can...

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Hlavní autoři: Mileyko, Yuriy, Joh, Richard I., Weitz, Joshua S.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575476/
https://ncbi.nlm.nih.gov/pubmed/18946033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806239105
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