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Acid phosphatase 5 is responsible for removing the mannose 6-phosphate recognition marker from lysosomal proteins
Most newly synthesized proteins destined for the lysosome reach this location via a specific intracellular pathway. In the Golgi, a phosphotransferase specifically labels lysosomal proteins with mannose 6-phosphate (Man-6-P). This modification is recognized by receptors that target the lysosomal pro...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575464/ https://ncbi.nlm.nih.gov/pubmed/18940929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807472105 |
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