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Using diastereopeptides to control metal ion coordination in proteins
Here, we report a previously undescribed approach for controlling metal ion coordination geometry in biomolecules by reorientating amino acid side chains through substitution of L- to D-amino acids. These diastereopeptides allow us to manipulate the spatial orientation of amino acid side chains to a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575460/ https://ncbi.nlm.nih.gov/pubmed/18940928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806792105 |
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