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In Silico Identification of Specialized Secretory-Organelle Proteins in Apicomplexan Parasites and In Vivo Validation in Toxoplasma gondii

Apicomplexan parasites, including the human pathogens Toxoplasma gondii and Plasmodium falciparum, employ specialized secretory organelles (micronemes, rhoptries, dense granules) to invade and survive within host cells. Because molecules secreted from these organelles function at the host/parasite i...

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Autors principals: Chen, ZhongQiang, Harb, Omar S., Roos, David S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575384/
https://ncbi.nlm.nih.gov/pubmed/18974850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003611
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