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Activation of DegP chaperone-protease via formation of large cage-like oligomers upon binding to substrate proteins

Cells use molecular chaperones and proteases to implement the essential quality control mechanism of proteins. The DegP (HtrA) protein, essential for the survival of Escherichia coli cells at elevated temperatures with homologues found in almost all organisms uniquely has both functions. Here we rep...

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Detalhes bibliográficos
Main Authors: Jiang, Jiansen, Zhang, Xuefeng, Chen, Yong, Wu, Yi, Zhou, Z. Hong, Chang, Zengyi, Sui, Sen-Fang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575304/
https://ncbi.nlm.nih.gov/pubmed/18697939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805464105
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