Membrane curvature induced by Arf1-GTP is essential for vesicle formation

The GTPase Arf1 is considered as a molecular switch that regulates binding and release of coat proteins that polymerize on membranes to form transport vesicles. Here, we show that Arf1-GTP induces positive membrane curvature and find that the small GTPase can dimerize dependent on GTP. Investigating...

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Dettagli Bibliografici
Autori principali: Beck, Rainer, Sun, Zhe, Adolf, Frank, Rutz, Chistoph, Bassler, Jochen, Wild, Klemens, Sinning, Irmgard, Hurt, Ed, Brügger, Britta, Béthune, Julien, Wieland, Felix
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575275/
https://ncbi.nlm.nih.gov/pubmed/18689681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805182105
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