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Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion

Understanding the pathways that control epithelial carcinogenesis is vital to the development of effective treatments. The Polycomb group family member Bmi1 is overexpressed in numerous epithelial tumors, but its role in their development has not been established. We now show a key role for Bmi1 in...

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Detalhes bibliográficos
Main Authors: Dovey, Jennifer Shepard, Zacharek, Sima J., Kim, Carla F., Lees, Jacqueline A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575250/
https://ncbi.nlm.nih.gov/pubmed/18697930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803574105
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